Androgen-Deprivation Therapy in Prostate Cancer and Cardiovascular Risk

Kode Jurnal : JMED-0001
Bahasa : Inggris
Kategori : Medis
Jumlah Halaman : 8 hal (PDF)
Harga : Rp 0,-
ABSTRAK
There is a substantial amount of data demonstrating that ADT adversely affects traditional cardiovascular risk factors, including serum lipoproteins, insulin sensitivity, and obesity. Recent studies have reported a relation in patients with prostate cancer between ADT and an increased risk of cardiovascular disease, although different studies both have and have not reported an increased risk of cardiovascular death. Whether the explanation for this discrepancy is related to issues regarding study design and study limitations, competing risk issues, or risk primarily confined to those with established coronary artery disease, or because there is no actual causal relation between ADT and cardiovascular events, cannot be determined definitively at this point. However, it is plausible that ADT could increase cardiovascular risk on the basis of its adverse impact on risk factors for cardiovascular disease.
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