Sunday, March 14, 2010

Evaluation of medical imaging systems

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Kode Jurnal : JMED-0003
Bahasa : Inggris
Kategori : Medis
Jumlah Halaman : 15 hal (PDF)
Harga : Rp 0,-
ABSTRAK
Medical imaging used to be primarily within the domain of radiology, but with the advent of virtual pathology slides and telemedicine, imaging technology is expanding in the healthcare enterprise. As new imaging technologies are developed, they must be evaluated to assess the impact and benefit on patient care. The authors review the hierarchical model of the efficacy of diagnostic imaging systems by Fryback and Thornbury Med. Decis. Making 11, 88–94 1991 as a guiding principle for system evaluation. Evaluation of medical imaging systems encompasses everything from the hardware and software used to acquire, store, and transmit images to the presentation of images to the interpreting clinician. Evaluation of medical imaging systems can take many forms, from the purely technical e.g., patient dose measurement to the increasingly complex e.g., determining whether a new imaging method saves lives and benefits society . Evaluation methodologies cover a broad range, from receiver operating characteristic ROC techniques that measure diagnostic accuracy to timing studies that measure image-interpretation workflow efficiency. The authors review briefly the history of the development of evaluation methodologies and review ROC methodology as well as other types of evaluation methods. They discuss unique challenges in system evaluation that face the imaging community today and opportunities for future advances. © 2008 American Association of Physicists in Medicine.
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Evolution of ultrasound physics and the role of medical physicists and the AAPM and its journal in that evolution

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Kode Jurnal : JMED-0002
Bahasa : Inggris
Kategori : Medis
Jumlah Halaman : 18 hal (PDF)
Harga : Rp 0,-
ABSTRAK
Ultrasound has been the greatest imaging modality worldwide for many years by equipment purchase value and by number of machines and examinations. It is becoming increasingly the front end imaging modality; serving often as an extension of the physician’s fingers. We believe that at the other extreme, high-end systems will continue to compete with all other imaging modalities in imaging departments to be the method of choice for various applications, particularly where safety and cost are paramount. Therapeutic ultrasound, in addition to the physiotherapy practiced for many decades, is just coming into its own as a major tool in the long progression to less invasive interventional treatment. The physics of medical ultrasound has evolved over many fronts throughout its history. For this reason, a topical review, rather than a primarily chronological one is presented. A brief review of medical ultrasound imaging and therapy is presented, with an emphasis on the contributions of medical physicists, the American Association of Physicists in Medicine AAPM and its publications, particularly its journal Medical Physics. The AAPM and Medical Physics have contributed substantially to training of physicists and engineers, medical practitioners, technologists, and the public. © 2009 American Association of Physicists in Medicine.
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Androgen-Deprivation Therapy in Prostate Cancer and Cardiovascular Risk

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Kode Jurnal : JMED-0001
Bahasa : Inggris
Kategori : Medis
Jumlah Halaman : 8 hal (PDF)
Harga : Rp 0,-
ABSTRAK
There is a substantial amount of data demonstrating that ADT adversely affects traditional cardiovascular risk factors, including serum lipoproteins, insulin sensitivity, and obesity. Recent studies have reported a relation in patients with prostate cancer between ADT and an increased risk of cardiovascular disease, although different studies both have and have not reported an increased risk of cardiovascular death. Whether the explanation for this discrepancy is related to issues regarding study design and study limitations, competing risk issues, or risk primarily confined to those with established coronary artery disease, or because there is no actual causal relation between ADT and cardiovascular events, cannot be determined definitively at this point. However, it is plausible that ADT could increase cardiovascular risk on the basis of its adverse impact on risk factors for cardiovascular disease.
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PENGELOLAAN SUMBERDAYA TIDAK PULIH BERBASIS EKONOMI SUMBERDAYA (STUDI KASUS : TAMBANG MINYAK BLOK CEPU )

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Kode Jurnal : JEE-0002
Bahasa : Indonesia
Kategori : Ekonomi
Jumlah Halaman : 14 hal (PDF)
Harga : Rp 0,-
ABSTRAK :
Rencana pengoperasian tambang minyak Blok Cepu menjadi perhatian publik menyusulberkembangnya opini bahwa pihak Indonesia dianggap tidak memegang kendali terhadap pengoperasian Blok Cepu. Pandangan ini tidak sepenuhnya benar mengingat bahwa seluruh kegiatan pengembangan lapangan tambang minyak di Blok Cepu dengan kandungan minyak cukup besar tersebut tetap harus dengan persetujuan Badan Pengelola Minyak dan Gas (BP Migas). Hal ini sebagai mana diatur dalam UU Migas No 22/2001, BP Migas merupakan lembaga yang memiliki wewenang untuk mengawasi kegiatan ekplorasi dan eksploitasi kegiatan migas hulu. Penulisan makalah ini dimaksud untuk mengkaji sistem pengelolaan tambang minyak untuk peningkatan kesejahteraan masyarakat berdasarkan pendekatan teori ekonomi sumberdaya (kelautan) sekaligus sarana aplikasi dalam mencermati permasalahan pengelolaan sumberdaya alam tak pulih.
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Systematic image-driven analysis of the spatial Drosophila embryonic expression landscape

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Kode Jurnal : JBIO-0001
Bahasa : Inggris
Kategori : BIOLOGI
Jumlah Halaman : 15 hal (PDF)
Harga : Rp 0,-
Discovery of temporal and spatial patterns of gene expression is essential for understanding the regulatory networks and development in multicellular organisms. We analyzed the images from our large-scale spatial expression data set of early Drosophila embryonic development and present a comprehensive computational image analysis of the expression landscape. For this study, we created an innovative virtual representation of embryonic expression patterns using an elliptically shaped mesh grid that allows us to make quantitative comparisons of gene expression using a common frame of reference. Demonstrating the power of our approach, we used gene co-expression to identify distinct expression domains in the early embryo; the result is surprisingly similar to the fate map determined using laser ablation. We also used a clustering strategy to find genes with similar patterns and developed new analysis tools to detect variation within consensus patterns, adjacent non-overlapping patterns, and anti-correlated patterns. Of the 1800 genes investigated, only half had previously assigned functions. The known genes suggest developmental roles for the clusters, and identification of related patterns predicts requirements for co-occurring biological functions.
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Saturday, March 13, 2010

Perhitungan Superposisi isodosis dalam Perencanaan Radioterapi

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Kode Jurnal : JFIS-0001
Bahasa : Indonesia
Kategori : FISIKA
Jumlah Halaman : 7 hal
Harga : Rp 0,-
Rangkuman :
Terapi irradiasi rotasional dapat mengurangi efek samping yang diterima oleh jaringan normal disekitar target / sasaran dan pengurangan efek samping ini terbesar jka target irradiasi berada di pusat obyek dan sebagai titik rotasi. Oleh karena itu untuk kasus jaringan abnormal yang letaknya tidak dipusat obyek, perlu ditambahkan bahan ekivalen jaringan (misalnya air) di sekitar obyek sehingga diperoleh geometri obyek simetri.
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Problem Behaviors and Personality of Children and Adolescents With Prader-Willi Syndrome

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Kode Jurnal : JPSIE-0010
Kategori : Psikologi
Jumlah Halaman : 10
Harga : Rp 0,-
ABSTRAK :
Objective: Compare behavioral and emotional problems of children and adolescents with Prader-Willi Syndrome (PWS) and dients consulting mental health centers (MHC) and related behavioral and emotional problems to the children's personality in the PWS group.
Methods: Participants were 39 children with PWS and 585 matched MHC dients. Child Behavior Checklist (CBCL) syndromes were related to the Big-Five personality factors measured with the California Child Q-sort (CCQ).
Results: Mean CBCL Total Problems scores were not different for the PWS and MHC groups, but differences were found for several of the CBCL subscales. Patterns of correlations among CBCL scales were similar In both groups, although coefficients were generally higher in the PWS group, indicating higher comorbidtty or co-absence of CBCL syndromes in children and adolescents with PWS. Personality profiles were specific for Internalizing and Externalizing problems of children and adolescents with PWS.
Key words: Prader-Willi Syndrome; Child Behavior Checklist (CBCL); California Child Q-sort (CCQ); Big Five personality factors; externalizing; internalizing.

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